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Post by Tony Crispino on Jan 1, 2014 22:27:13 GMT -8
This is an interview of the primary investigator of the Xofigo trials that led to the drugs approval. Dr. Nicholas Vogelzang is also Scientific Review Board member here at PCAF. In this video Dr. V. speaks about the success with Radium-223 dichloride now released under the brand name Xofigo:
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Jerry
Junior Member
Posts: 44 
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Post by Jerry on Jan 2, 2014 16:33:08 GMT -8
Thanks for the video. I'm glad I now know how to pronounce Xofigo.
Xofigo is only available for CRPC patients, correct? If so, what is the roadmap to get it out there for PC patients that are not CRPC?
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Post by Tony Crispino on Jan 2, 2014 18:59:00 GMT -8
Jerry in the standard of care established by the NCCN Doctors Guidelines you can see how it's broken down. But it's important to remember that these guidelines are "standard" of care on not individually defined personalized care. You can check them out in the thread labeled "NCCN Patient Guidelines" it's a file posted by are great friend, Allen! advancedpcatalk.freeforums.net/thread/32/nccn-patient-guidelinesTony |
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Jerry
Junior Member
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Post by Jerry on Jan 2, 2014 19:30:03 GMT -8
Wow....that's going to be a good read...I think I just concluded that I'm glad that I have a team of good docs looking out for what's best for me...and can take all this into consideration.
Looks like after a quick review that xofigo is for CRPC guys with just bone mets...
wish these drugs were approved for earlier use...drives me crazy...
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Post by Tony Crispino on Jan 2, 2014 19:47:44 GMT -8
To do so Jerry requires an extensive trial process to verify it's the right thing to do to serve them up sooner. As Nick said in the video this is "liquid radiation". The harms exist in patients with shorter life expectancy but they are negligible compared to the cancer. But if a cancer is not an immediate threat the long term effects of Radium-223 are not clear.
I know you get it. The drug needs to be proven in other settings to be safe. Nick is the guy to talk to about it. Call him. He'll let you know what you already suspect.
Tony
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Jerry
Junior Member
Posts: 44
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Post by Jerry on Jan 2, 2014 20:02:50 GMT -8
Find the drug fascinating...and seems to be a better option, and perhaps less harmful, then my current spot radiation plan...that is, when something is identified...
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