Post by Tony Crispino on Apr 30, 2016 10:15:36 GMT -8
A couple great slides at SWOG presented by ASCO discuss the dynamics of clinical trial funding. I was only able to photo them yesterday but here's the gist of them. Trials are funded in two ways ~ commercially and publicly. Here are the basic differences in goals:
| Commercially Funded Trials | Publicly Funded Trials |
| New Drug Registration | Optimize Treatment Therapies |
| Label Extension | Label Extension |
| Expand Market Share | Create New Knowledge |
| Create Shareholder Value | Improve Public Health |
Publicly funded clinical trials are essential to:
- Directly compare drug treatments
- Develop combined modality treatment.
- Study chemo-prevention and rare diseases
- Identify patient subsets
- Study health outcomes, cost, and cost effectiveness
- Define the role of precision medicine approaches in cancer management
Cooperative Value in Trials
SWOG is celebrating 60 years in cancer research through both private and public funding. SWOG itself is administratively funded through the Hope Foundation which is a non-profit cancer research group. Through this way SWOG remains unbiased and neutral on its clinical trials. The Genitourinary Committee, that I am privileged to serve on, has the most prostate cancer standard of care changing trials than any other cooperative.
Examples of Privately Trialed Drugs at SWOG:
TAX327 - docetaxel
Radium 223
Abiraterone
Enzalutamide
Cabazitaxel
Examples of Publicly Funded Trials at SWOG (Or in cooperation with another Co-Op)
E3805 CHARTED This trial funded by NCI was originally funded by Sanofi Aventis.
SELECT
PCPT
- Directly compare drug treatments
- Develop combined modality treatment.
- Study chemo-prevention and rare diseases
- Identify patient subsets
- Study health outcomes, cost, and cost effectiveness
- Define the role of precision medicine approaches in cancer management
Cooperative Value in Trials
SWOG is celebrating 60 years in cancer research through both private and public funding. SWOG itself is administratively funded through the Hope Foundation which is a non-profit cancer research group. Through this way SWOG remains unbiased and neutral on its clinical trials. The Genitourinary Committee, that I am privileged to serve on, has the most prostate cancer standard of care changing trials than any other cooperative.
Examples of Privately Trialed Drugs at SWOG:
TAX327 - docetaxel
Radium 223
Abiraterone
Enzalutamide
Cabazitaxel
Examples of Publicly Funded Trials at SWOG (Or in cooperation with another Co-Op)
E3805 CHARTED This trial funded by NCI was originally funded by Sanofi Aventis.
SELECT
PCPT