Post by Tony Crispino on Dec 21, 2013 8:06:06 GMT -8
This post is from the ASCO December 6 wire
Genetic Mutation May Play a Role in Worse Outcomes for Obese Prostate Cancer Patients
Key Points:
Genetic Mutation May Play a Role in Worse Outcomes for Obese Prostate Cancer Patients
Key Points:
- Overweight or obese men with prostate cancer whose tumors were positive for the TMPRSS2:ERG genetic mutation had a more than 50% increased risk of dying from cancer after their diagnosis compared with normal-weight men.\
- Obesity had no effect on cancer survival among men whose tumors did not have the mutation.
- Men whose tumors contained the TMPRSS2:ERG genetic mutation also had higher levels of the receptors for insulin and growth factor.
Tony